Recombinant CRTC2 anticorps

N° du produit ABIN7880510

Cet anticorps Lapin Monoclonal détecte spécifiquement CRTC2 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant CRTC2 anticorps (ABIN7880510)

Antigène: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CRTC2 est non-conjugé

Application: Western Blotting (WB)

Clone: 28C77

Détail du produit anti-CRTC2 anticorps

Fonction: CRTC2 Antibody / TORC2

Purification: Affinity chromatography

Immunogène: A synthetic peptide from human CREB-regulated transcription coactivator 2 protein was used as the immunogen for the CRTC2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CRTC2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the CRTC2 antibody at -20oC.

Détails sur CRTC2

Antigène: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Autre désignation: CRTC2

Sujet: CRTC2 is a transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. [UniProt]

UniProt: Q53ET0

Pathways: AMPK Signaling, Carbohydrate Homeostasis