DPYSL2 anticorps
Aperçu rapide pour DPYSL2 anticorps (ABIN7880629)
Antigène
Voir toutes DPYSL2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- CRMP2 Antibody / DPYSL2
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Purification
- Antigen affinity purified
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Immunogène
- Amio acids KDRFQLTDCQIYEVLSV were used as the immunogen for the CRMP2 antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the CRMP2 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the CRMP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))
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Autre désignation
- CRMP2
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Sujet
- Dihydropyrimidinase-related protein 2, also called Collapsin response mediator protein 2 (CRMP2), is an enzyme that in humans is encoded by the DPYSL2 gene. This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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UniProt
- Q16555
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Pathways
- Regulation of Cell Size
Antigène
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