ELANE anticorps
Aperçu rapide pour ELANE anticorps (ABIN7880674)
Antigène
Voir toutes ELANE AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Neutrophil Elastase Antibody
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Purification
- Affinity purified
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Immunogène
- A synthetic peptide specific to human Neutrophil Elastase / ELANE was used as the immunogen for the Neutrophil Elastase antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the Neutrophil Elastase antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store the Neutrophil Elastase antibody at -20oC.
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- ELANE (Elastase, Neutrophil Expressed (ELANE))
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Autre désignation
- Neutrophil Elastase
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Sujet
- Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. [RefSeq]
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UniProt
- P08246
Antigène
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