Cet anticorps anti-ELANE Monoclonal Lapin (Clone AOCI-5) (ABIN7880674) détecte spécifiquement ELANE dans WB.
L’anticorps est réactif avec des échantillons de Humain.
ELANE
Reactivité: Souris, Rat
WB, ELISA, IHC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Optimal dilution of the Neutrophil Elastase antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Buffer
Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store the Neutrophil Elastase antibody at -20oC.
Antigène
ELANE
(Elastase, Neutrophil Expressed (ELANE))
Autre désignation
Neutrophil Elastase
Sujet
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. [RefSeq]