ELP3/KAT9 anticorps

N° du produit ABIN7880676

L’anticorps anti-ELP3/KAT9 Monoclonal Souris est utilisé pour la détection de ELP3/KAT9 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour ELP3/KAT9 anticorps (ABIN7880676)

Antigène: ELP3/KAT9 (ELP3) (Elongator complex protein 3 (ELP3))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ELP3/KAT9 est non-conjugé

Application: Western Blotting (WB)

Clone: 8B4

Détail du produit anti-ELP3/KAT9 anticorps

Fonction: Elongator complex protein 3 Antibody / ELP3 / KAT9

Séquence: RDPTKFQHQG FGMLLMEEAE RIAREEH

Purification: Antigen affinity purified

Immunogène: Amino acids RDPTKFQHQGFGMLLMEEAERIAREEH were used as the immunogen for the Elongator complex protein 3 antibody.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal dilution of the Elongator complex protein 3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Elongator complex protein 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur ELP3/KAT9

Antigène: ELP3/KAT9 (ELP3) (Elongator complex protein 3 (ELP3))

Autre désignation: Elongator complex protein 3

Sujet: Elongator complex protein 3, also named KAT9, is a protein that in humans is encoded by the ELP3 gene. It is mapped to 8p21.1. ELP3 is the catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. ELP3 supports the migration and branching of projection neurons through acetylation of alpha-tubulin in the developing cerebral cortex. In mammals, ELP3 is important for paternal DNA demethylationafterfertilization.ELP3 is potentially involved in cellular redox homeostasis by mediating the acetylation ofglucose-6-phosphate dehydrogenase. Besides, ELP3 may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.

UniProt: Q9H9T3