Recombinant EMC4 anticorps

N° du produit ABIN7880733

L’anticorps anti-EMC4 Monoclonal Lapin est utilisé pour la détection de EMC4 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC et IP.

Aperçu rapide pour Recombinant EMC4 anticorps (ABIN7880733)

Antigène: EMC4 (ER Membrane Protein Complex Subunit 4 (EMC4))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp EMC4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: 30E32

Détail du produit anti-EMC4 anticorps

Fonction: EMC4 Antibody / ER membrane protein complex subunit 4

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human EMC4 was used as the immunogen for the EMC4 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the EMC4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the EMC4 antibody at -20oC.

Détails sur EMC4

Antigène: EMC4 (ER Membrane Protein Complex Subunit 4 (EMC4))

Autre désignation: EMC4

Sujet: EMC4 antibody recognizes ER membrane protein complex subunit 4, a component of the endoplasmic reticulum membrane complex (EMC). The EMC facilitates insertion of transmembrane proteins into the ER and aids in proper folding of multipass proteins. EMC4 plays a role in maintaining ER homeostasis and ensuring the quality control of membrane protein biosynthesis.

Research with EMC4 antibody has shown that loss of EMC function leads to defective protein targeting, ER stress, and activation of the unfolded protein response. EMC4 has also been linked to viral infection processes, where certain viruses hijack EMC components to ensure proper expression of their envelope proteins. These findings highlight EMC4's importance in both normal physiology and infectious disease biology.

Antibodies against EMC4 are validated in assays such as western blot, immunohistochemistry, and immunofluorescence. These reagents provide reliable detection of EMC4, allowing researchers to investigate ER protein insertion pathways and responses to cellular stress.

NSJ Bioreagents provides this EMC4 antibody for research on ER biology, membrane protein folding, and host-pathogen interactions. Alternate names include ER membrane protein complex subunit 4 antibody, EMC4A antibody, and transmembrane protein 93 antibody.

UniProt: Q5J8M3