F11R anticorps
Aperçu rapide pour F11R anticorps (ABIN7880760)
Antigène
Voir toutes F11R AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- F11R Antibody / JAM-A
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Séquence
- RVEWKFDQGD TTRLVCYNNK
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Purification
- Affinity purified
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Immunogène
- Amino acids RVEWKFDQGDTTRLVCYNNK from the human protein were used as the immunogen for the F11R antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the F11R antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the F11R antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- F11R (F11 Receptor (F11R))
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Autre désignation
- F11R
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Sujet
- Junctional adhesion molecule A is a protein that in humans is encoded by the F11R gene. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
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UniProt
- Q9Y624
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Pathways
- Cell-Cell Junction Organization
Antigène
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