FGA anticorps
Aperçu rapide pour FGA anticorps (ABIN7880784)
Antigène
Voir toutes FGA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Fonction
- Fibrinogen Alpha Chain Antibody (azide and preservative free)
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Purification
- PEG precipitation
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Immunogène
- Human acute monoblastic leukemia cells were used as the immunogen for the Fibrinogen Alpha Chain antibody.
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Isotype
- IgM, kappa
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Indications d'application
- Optimal dilution of the Fibrinogen Alpha Chain antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the Fibrinogen Alpha Chain antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- FGA (Fibrinogen alpha Chain (FGA))
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Autre désignation
- Fibrinogen Alpha Chain
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Sujet
- The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits. Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types.
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UniProt
- P02671
Antigène
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