FUS anticorps
Aperçu rapide pour FUS anticorps (ABIN7880833)
Antigène
Voir toutes FUS AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Fonction
- TLS Antibody / Translocated in liposarcoma protein / FUS
-
Séquence
- ENVTIESVAD YFKQ
-
Purification
- Antigen affinity purified
-
Immunogène
- Amino acids ENVTIESVADYFKQ from the human protein were used as the immunogen for the TLS antibody.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal dilution of the TLS antibody should be determined by the researcher.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- After reconstitution, the TLS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- FUS (Fused in Sarcoma (FUS))
-
Autre désignation
- TLS
-
Sujet
- RNA-binding protein FUS/TLS (Fused in Sarcoma/Translocated in Sarcoma) is a protein that in humans is encoded by the FUS gene. This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.
-
UniProt
- P35637
Antigène
-