Ghrelin anticorps

N° du produit ABIN7880867

Cet anticorps Lapin Polyclonal détecte spécifiquement Ghrelin dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Ghrelin anticorps (ABIN7880867)

Antigène: Ghrelin (GHRL)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ghrelin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Ghrelin anticorps

Fonction: Ghrelin Antibody / GHRL

Purification: Antigen affinity purified

Immunogène: the Ghrelin antibody can be stored for up to one month at 4oC. For long-term

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Ghrelin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Ghrelin

Antigène: Ghrelin (GHRL)

Autre désignation: Ghrelin

Sujet: This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression.,Amino acids QRKESKKPPAKLQPR from the human protein were used as the immunogen for the Ghrelin antibody.,After reconstitution

UniProt: Q9UBU3

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Negative Regulation of Hormone Secretion, Synaptic Membrane, Feeding Behaviour