GSTA3 anticorps

N° du produit ABIN7880893

Cet anticorps anti-GSTA3 Polyclonal Lapin (ABIN7880893) détecte spécifiquement GSTA3 dans WB et FACS. L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour GSTA3 anticorps (ABIN7880893)

Antigène: GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTA3 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-GSTA3 anticorps

Fonction: Gsta3 Antibody

Séquence: EFEEKFLKTR DDLARLRSD

Purification: Affinity purified

Immunogène: Amino acids EFEEKFLKTRDDLARLRSD from the mouse protein were used as the immunogen for the Gsta3 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Gsta3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Gsta3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur GSTA3

Antigène: GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))

Autre désignation: Gsta3

Sujet: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined.

UniProt: P30115