CD235a/GYPA anticorps

N° du produit ABIN7880907

L’anticorps anti-CD235a/GYPA Monoclonal Souris est utilisé pour la détection de CD235a/GYPA dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour CD235a/GYPA anticorps (ABIN7880907)

Antigène: CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD235a/GYPA est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SPM599

Détail du produit anti-CD235a/GYPA anticorps

Fonction: Anti-Glycophorin A Antibody

Purification: Protein G affinity chromatography

Immunogène: Recombinant human GPA protein was used as the immunogen for the anti-Glycophorin A antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the anti-Glycophorin A antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the anti-Glycophorin A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur CD235a/GYPA

Antigène: CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

Autre désignation: Glycophorin A

Sujet: Recognizes a sialoglycoprotein of 39 kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

UniProt: P02724

Pathways: Maintenance of Protein Location