Golgi Marker anticorps (CF®488A)

N° du produit ABIN7880922

L’anticorps anti-Golgi Marker Monoclonal Souris est utilisé pour la détection de Golgi Marker dans des échantillons de Humain. Il a été validé pour FACS et IF.

Aperçu rapide pour Golgi Marker anticorps (CF®488A) (ABIN7880922)

Antigène: Golgi Marker

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: CF®488A

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: GLG1-970

Détail du produit

Fonction: Golgi Marker Antibody

Purification: Protein G affinity chromatography

Immunogène: The Golgi fraction from human liver cells was used as the immunogen for the Golgi Marker antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Golgi Marker antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 500 µL at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the Golgi Marker antibody at 2-8oC, protected from light.

Détail du antigène

Antigène: Golgi Marker

Sujet: This MAb recognizes a protein of 134 kDa, which binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils). Fucosylation is essential for binding to E-selectin. It contains sialic acid residues and 16 Cys-rich GLG1 repeats. Highest levels are expressed in pancreas, skeletal muscle, placenta, heart, testis and ovary. It is also found in the kidney, liver, lung and brain. It is expressed in both adult and fetal tissues. This MAb can be used to stain the Golgi complex in cell or tissue preparations and can be used as a Golgi marker in subcellular fractions. It produces a diffuse staining pattern of the Golgi zone in normal and malignant cells. This MAb is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells. The Golgi apparatus is an organelle present in all eukaryotic cells that forms a part of the endomembrane system. The primary function of the Golgi apparatus is to process and package macromolecules synthesized by the cell for exocytosis or use within the cell. The Golgi is made up of a stack of flattened, membrane-bound sacs known as cisternae, with three functional regions: the cis face, medial region and trans face. Each region consists of various enzymes that selectively modify the macromolecules passing though them, depending on where they are destined to reside. Several spherical vesicles that have budded off of the Golgi are present surrounding the main cisternae. The Golgi tends to be more pronounced and numerous in cells that make and secrete many substances such as plasma B cells.

UniProt: Q92896