Cet anticorps anti-IGF2BP3 Monoclonal Lapin (Clone AEDB-9) (ABIN7881187) détecte spécifiquement IGF2BP3 dans WB.
L’anticorps est réactif avec des échantillons de Humain.
Optimal dilution of the IGF2BP3 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Buffer
Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store the IGF2BP3 antibody at -20oC.
Antigène
IGF2BP3
(Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))
Autre désignation
IGF2BP3
Sujet
RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. [UniProt]