ICAM-3/CD50 anticorps

N° du produit ABIN7881232

Cet anticorps anti-ICAM-3/CD50 Monoclonal Souris (Clone SPM505) (ABIN7881232) détecte spécifiquement ICAM-3/CD50 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ICAM-3/CD50 anticorps (ABIN7881232)

Antigène: ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ICAM-3/CD50 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SPM505

Détail du produit anti-ICAM-3/CD50 anticorps

Fonction: Anti-ICAM-3 Antibody

Purification: Protein G affinity chromatography

Immunogène: Stimulated human leukocytes were used as the immunogen for the anti-ICAM-3 antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the anti-ICAM-3 antibody should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 minutes
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the anti-ICAM-3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur ICAM-3/CD50

Antigène: ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))

Autre désignation: ICAM-3

Sujet: Recognizes the D1 domain of an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This mAb is excellent for staining of formalin/paraffin tissues.

UniProt: P32942