IRF1 anticorps

N° du produit ABIN7881245

Cet anticorps Lapin Monoclonal détecte spécifiquement IRF1 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour IRF1 anticorps (ABIN7881245)

Antigène: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp IRF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: DHE-9

Détail du produit anti-IRF1 anticorps

Fonction: IRF1 Antibody / Interferon regulatory factor 1

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human Interferon regulatory factor 1 was used as the immunogen for the IRF1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the IRF1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the IRF1 antibody at -20oC.

Détails sur IRF1

Antigène: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Autre désignation: IRF1

Sujet: The protein encoded by the IRF1 gene is a transcriptional regulator and tumor suppressor, serving as an activator of genes involved in both innate and acquired immune responses. The encoded protein activates the transcription of genes involved in the body's response to viruses and bacteria, playing a role in cell proliferation, apoptosis, the immune response, and DNA damage response. This protein represses the transcription of several other genes. As a tumor suppressor, it both suppresses tumor cell growth and stimulates an immune response against tumor cells. Defects in this gene have been associated with gastric cancer, myelogenous leukemia, and lung cancer. [RefSeq]

UniProt: P10914

Pathways: Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy