IL-25 anticorps
Aperçu rapide pour IL-25 anticorps (ABIN7881298)
Antigène
Voir toutes IL-25 (IL25) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Fonction
- IL-25 Antibody / IL-17E (azide and preservative free)
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Purification
- Protein A/G affinity
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Immunogène
- A recombinant protein fragment was used as the immunogen for the IL-25 antibody.
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal dilution of the IL-25 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Agent conservateur
- Azide free
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the IL-25 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IL-25 (IL25) (Interleukin 25 (IL25))
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Autre désignation
- IL-25
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Sujet
- Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. Interleukin-17 (IL-17) and its cognate receptor, IL-17R, are an example of such a cytokine receptor pair. Originally identified as a rodent cDNA termed CTLA8, IL-17 is capable of inducing the secretion of IL-6 and IL-8 and augmenting the expression of ICAM-1 in human fibroblast cultures. The IL-17 protein exhibits a striking degree of homology with the HSV-13 protein which mimics its function. The IL-17 receptor is a type I transmembrane protein 864 amino acids in length that is highly expressed in spleen and kidney.
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UniProt
- Q9H293
Antigène
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