Recombinant CDH6 anticorps

N° du produit ABIN7881340

L’anticorps anti-CDH6 Monoclonal Lapin est utilisé pour la détection de CDH6 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant CDH6 anticorps (ABIN7881340)

Antigène: CDH6 (K-Cadherin (CDH6))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CDH6 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CDH6-9300R

Détail du produit anti-CDH6 anticorps

Fonction: Recombinant K-Cadherin Antibody / Cadherin 6 / CDH6

Purification: Protein A/G affinity

Immunogène: Recombinant human Cadherin 6 protein (CDH6) was used as the immunogen for the recombinant K-Cadherin antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant K-Cadherin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant K-Cadherin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur CDH6

Antigène: CDH6 (K-Cadherin (CDH6))

Autre désignation: K-Cadherin

Sujet: This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion. This protein may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.

UniProt: P55285

Pathways: Cell-Cell Junction Organization