L1CAM anticorps

N° du produit ABIN7881450

Cet anticorps Souris Monoclonal détecte spécifiquement L1CAM dans ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour L1CAM anticorps (ABIN7881450)

Antigène: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp L1CAM est non-conjugé

Application: ELISA

Clone: SPM275

Détail du produit anti-L1CAM anticorps

Fonction: L1CAM Antibody / NCAM-L1 / CD171

Purification: Protein A/G affinity

Immunogène: Homogenous suspension of 16-week human fetal brain cells were used as the immunogen for the L1CAM antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the L1CAM antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the L1CAM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur L1CAM

Antigène: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Autre désignation: L1CAM

Sujet: Recognizes a cell surface protein of 220-240 kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius), 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs), and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.

UniProt: P32004

Pathways: Synaptic Membrane