NG2 anticorps

N° du produit ABIN7881590

Cet anticorps anti-NG2 Monoclonal Souris (Clone LHM 2) (ABIN7881590) détecte spécifiquement NG2 dans IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour NG2 anticorps (ABIN7881590)

Antigène: NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NG2 est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: LHM 2

Détail du produit anti-NG2 anticorps

Fonction: CSPG4 Antibody / NG2

Purification: Protein G affinity chromatography

Immunogène: A 375P cells crude extract was used as the immunogen for this CSPG4 antibody

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the CSPG4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the CSPG4 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur NG2

Antigène: NG2 (MCSP) (Melanoma Associated Chondroitin Sulfate Proteoglycan (MCSP))

Autre désignation: CSPG4

Sujet: Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin. Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades. [UniProt]

UniProt: Q6UVK1

Pathways: Glycosaminoglycan Metabolic Process