MBD3 anticorps

N° du produit ABIN7881628

L’anticorps anti-MBD3 Monoclonal Lapin est utilisé pour la détection de MBD3 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour MBD3 anticorps (ABIN7881628)

Antigène: MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MBD3 est non-conjugé

Application: Western Blotting (WB)

Clone: AFEE-13

Détail du produit anti-MBD3 anticorps

Fonction: MBD3 Antibody

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human MBD3 was used as the immunogen for the MBD3 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the MBD3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the MBD3 antibody at -20oC.

Détails sur MBD3

Antigène: MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

Autre désignation: MBD3

Sujet: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. The MBD3 gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. [RefSeq]

UniProt: O95983

Pathways: Chromatin Binding