MFN2 anticorps

N° du produit ABIN7881650

Cet anticorps anti-MFN2 Monoclonal Lapin (Clone AOCA-13) (ABIN7881650) détecte spécifiquement MFN2 dans WB. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour MFN2 anticorps (ABIN7881650)

Antigène: MFN2 (Mitofusin 2 (MFN2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MFN2 est non-conjugé

Application: Western Blotting (WB)

Clone: AOCA-13

Détail du produit anti-MFN2 anticorps

Fonction: Mitofusin 2 Antibody / MFN2

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human Mitofusin 2 / MFN2 was used as the immunogen for the Mitofusin 2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Mitofusin 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the Mitofusin 2 antibody at -20oC.

Détails sur MFN2

Antigène: MFN2 (Mitofusin 2 (MFN2))

Autre désignation: Mitofusin 2

Sujet: Mitofusin 2 is a mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks. Membrane clustering requires GTPase activity and may involve a major rearrangement of the coiled coil domains (Probable). Plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PRKN recruitment to dysfunctional mitochondria. [UniProt]

UniProt: O95140

Pathways: Skeletal Muscle Fiber Development