MUC2 anticorps

N° du produit ABIN7881672

Cet anticorps Souris Monoclonal détecte spécifiquement MUC2 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour MUC2 anticorps (ABIN7881672)

Antigène: MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MUC2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SPM296

Détail du produit anti-MUC2 anticorps

Fonction: MUC2 Antibody

Séquence: KYPTTTPIST TTMVTPTPTP TGTQTPTTT

Purification: Protein G affinity chromatography

Immunogène: Amino acids KYPTTTPISTTTMVTPTPTPTGTQTPTTT from the human protein were used as the immunogen for this MUC2 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: The optimal dilution of the MUC2 antibody for each application should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9, for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the MUC2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur MUC2

Antigène: MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

Autre désignation: MUC2

Sujet: Recognizes a single glycoprotein of 520 kDa, identified as mucin 2 (MUC2). This mAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon, in about 65 % of colonic carcinomas and about 40 % of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.

UniProt: Q02817