MSTN anticorps

N° du produit ABIN7881742

L’anticorps anti-MSTN Polyclonal Lapin est utilisé pour la détection de MSTN dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour MSTN anticorps (ABIN7881742)

Antigène: MSTN (Myostatin (MSTN))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MSTN est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MSTN anticorps

Fonction: GDF8 Antibody / Myostatin

Séquence: SGECEFVFLQ KYPH

Purification: Affinity purified

Immunogène: Amino acids SGECEFVFLQKYPH from the human protein were used as the immunogen for the GDF8 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the GDF8 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the GDF8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur MSTN

Antigène: MSTN (Myostatin (MSTN))

Autre désignation: GDF8

Sujet: Myostatin (also known as growth differentiation factor 8, abbreviated GDF-8) is a myokine, a protein produced and released by myocytes that acts on muscle cells' autocrine function to inhibit myogenesis: muscle cell growth and differentiation. In humans it is encoded by the MSTN gene. This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals.

UniProt: O14793