Recombinant Nkx2-2 anticorps
Aperçu rapide pour Recombinant Nkx2-2 anticorps (ABIN7881815)
Antigène
Voir toutes Nkx2-2 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Recombinant NKX2.2 Antibody / Rabbit Monoclonal
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Purification
- Protein A affinity chromatography
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Immunogène
- A human partial recombinant protein was used as the immunogen for this recombinant NKX2.2 antibody.
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Isotype
- IgG, kappa
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Indications d'application
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Titering of the recombinant NKX2.2 antibody may be required for optimal performance.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store the recombinant NKX2.2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
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Autre désignation
- NKX2.2
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Sujet
- NKX2.2 acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter (By similarity). [UniProt]
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Pathways
- Dopaminergic Neurogenesis
Antigène
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