Nuclear Antigen anticorps

N° du produit ABIN7881829

L’anticorps anti-Nuclear Antigen Monoclonal Souris est utilisé pour la détection de Nuclear Antigen dans des échantillons de Humain, Souris et Rat. Il a été validé pour IHC (p).

Aperçu rapide pour Nuclear Antigen anticorps (ABIN7881829)

Antigène: Nuclear Antigen (IPO-38)

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Nuclear Antigen est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SPM515

Détail du produit anti-Nuclear Antigen anticorps

Fonction: IPO38 Antibody (Proliferation Marker)

Purification: PEG precipitation

Immunogène: Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the IPO38 antibody.

Isotype: IgM, kappa

Information d'application

Indications d'application: Optimal dilution of the IPO38 antibody should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the IPO38 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Nuclear Antigen

Antigène: Nuclear Antigen (IPO-38)

Autre désignation: IPO38

Sujet: Recognizes a protein of 14-16 kDa, which is a novel nuclear antigen of proliferating cells. IPO-38 antigen is present in the nuclei of proliferating cells such as Hodgkin s disease and non-Hodgkin s lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO-38 can be a useful marker of cell proliferation during monitoring of tumor progression.