NFIA anticorps

N° du produit ABIN7881835

L’anticorps anti-NFIA Monoclonal Souris est utilisé pour la détection de NFIA dans des échantillons de Humain. Il a été validé pour WB, IF, FACS et IHC (p).

Aperçu rapide pour NFIA anticorps (ABIN7881835)

Antigène: NFIA (Nuclear Factor I/A (NFIA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NFIA est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PCRP-NFIA-2C6

Détail du produit anti-NFIA anticorps

Fonction: NFIA Antibody / Nuclear Factor 1 A

Purification: Protein A/G affinity

Immunogène: A recombinant protein fragment was used as the immunogen for the NFIA antibody.

Isotype: IgG2c

Information d'application

Indications d'application: Optimal dilution of the NFIA antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the NFIA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur NFIA

Antigène: NFIA (Nuclear Factor I/A (NFIA))

Autre désignation: NFIA

Sujet: Nuclear factor (NF) proteins are a family of CCAAT-box-binding proteins that stimulate DNA replication and activate transcription. Analysis of human NF-1 messenger RNA has revealed two forms of the NF-1 protein arising from an alternate splicing of a single NF-1 gene. NF-1 binds its consensus DNA element as a homodimer via an amino-terminal DNA-binding domain, and activates transcription through a putatively novel, proline-rich, carboxy-terminal transactivation domain. The NF-1 protein has been shown to recognize and bind the adenovirus type 2 promoter and activate transcription of herpes simplex virus thymidine kinase genes. The NF-1 consensus element has been found in the upstream promoter region of myriad eukaryotic genes, including that of Ha-Ras, -globin, HSP 70, GRP 78, Histone H1, myelin basic protein and in the Xenopus laevis vitellogenin gene promoter.

UniProt: Q12857