ODC1 anticorps

N° du produit ABIN7881883

L’anticorps anti-ODC1 Monoclonal Souris est utilisé pour la détection de ODC1 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour ODC1 anticorps (ABIN7881883)

Antigène: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ODC1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SPM565

Détail du produit anti-ODC1 anticorps

Fonction: Ornithine Decarboxylase Antibody

Purification: Protein G affinity chromatography

Immunogène: Recombinant human protein was used as the immunogen for this ODC-1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: The optimal dilution of the Ornithine Decarboxylase antibody for each application should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Ornithine Decarboxylase antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur ODC1

Antigène: ODC1 (Ornithine Decarboxylase 1 (ODC1))

Autre désignation: Ornithine Decarboxylase

Sujet: Recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

UniProt: P11926