PHPT1 anticorps

N° du produit ABIN7881936

Cet anticorps Souris Monoclonal détecte spécifiquement PHPT1 dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PHPT1 anticorps (ABIN7881936)

Antigène: PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PHPT1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PHPT1-12054

Détail du produit anti-PHPT1 anticorps

Fonction: Phosphohistidine phosphatase 1 Antibody / PHPT1

Purification: Protein A/G affinity

Immunogène: A recombinant human 14 kDa phosphohistidine phosphatase protein was used as the immunogen for the Phosphohistidine phosphatase 1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Phosphohistidine phosphatase 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Phosphohistidine phosphatase 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur PHPT1

Antigène: PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))

Autre désignation: Phosphohistidine phosphatase 1

Sujet: PHPT1 (phosphohistidine phosphatase 1), also known as 14 kDa phosphohistidine phosphatase, is a 125 amino acid enzyme belonging to the Janus protein family. Existing as a monomer in the cytoplasm, PHPT1 is an EDTAinsensitive phosphohistidine phosphatase. First identified in human adrenal gland, PHPT1 is highly expressed in skeletal muscle and heart, with lower expression in liver, pancreas and kidney. Overexpression of PHPT1 leads to specific phosphohistidine phosphatase activity towards phosphopeptide I, with no activity detected towards phosphotyrosine, phosphothreonine and phosphoserine peptides. PHPT1 is highly conserved among species, suggesting that it serves an essential functional role.

UniProt: Q9NRX4

Pathways: Positive Regulation of Peptide Hormone Secretion