PIM1 anticorps
Aperçu rapide pour PIM1 anticorps (ABIN7881952)
Antigène
Voir toutes PIM1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- PIM1 Antibody
-
Purification
- Affinity purified
-
Immunogène
- A synthetic peptide specific to human PIM1 was used as the immunogen for the PIM1 antibody.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal dilution of the PIM1 antibody should be determined by the researcher.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store the PIM1 antibody at -20oC.
-
-
- PIM1 (Pim-1 Oncogene (PIM1))
-
Autre désignation
- PIM1
-
Sujet
- The protein encoded by the PIM1 gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons. [RefSeq]
-
UniProt
- P11309
-
Pathways
- Glycosaminoglycan Metabolic Process
Antigène
-