Podoplanin anticorps

N° du produit ABIN7881985

L’anticorps anti-Podoplanin Monoclonal Souris est utilisé pour la détection de Podoplanin dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Podoplanin anticorps (ABIN7881985)

Antigène: Podoplanin (PDPN)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Podoplanin est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: D2-40

Détail du produit anti-Podoplanin anticorps

Fonction: Podoplanin Antibody

Purification: Protein G affinity

Immunogène: Resected tissue from dysgeminoma of the ovary was used as the immunogen for the Podoplanin antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Podoplanin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the Podoplanin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Podoplanin

Antigène: Podoplanin (PDPN)

Autre désignation: Podoplanin

Sujet: Podoplanin is a transmembrane mucoprotein (38 kDa) recognized by the D2-40 monoclonal antibody. Podoplanin is specifically expressed in the endothelium of lymphatic capillaries but not in the blood vasculature. In normal skin and kidney, podoplanin is co-localized with VEGFR3/FLT4, another marker for lymphatic endothelial cells. Podoplanin is selectively expressed in lymphatic endothelium as well as Lymphangiomas, Kaposi’s Sarcomas and in subset Angiosarcomas with probable lymphatic differentiation. Podoplanin has also been shown to be expressed in Epithelioid Mesotheliomas, Hemangioblastomas and Seminomas.

UniProt: Q86YL7

Pathways: Dicarboxylic Acid Transport