Cet anticorps anti-Podoplanin Monoclonal Lapin (Clone PDPN-8950R) (ABIN7881986) détecte spécifiquement Podoplanin dans WB et IHC (p).
L’anticorps est réactif avec des échantillons de Humain.
Optimal dilution of the Podoplanin antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Agent conservateur
Azide free
Stock
-20 °C
Stockage commentaire
Aliquot the Podoplanin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Antigène
Podoplanin (PDPN)
Autre désignation
Podoplanin
Sujet
It recognizes a muco-protein of 38-43 kDa, which is identified as Podoplanin (PDPN), also called Glycoprotein 36 (Gp36). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.