Recombinant P4HTM anticorps

N° du produit ABIN7882047

Cet anticorps Lapin Monoclonal détecte spécifiquement P4HTM dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant P4HTM anticorps (ABIN7882047)

Antigène: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp P4HTM est non-conjugé

Application: Western Blotting (WB)

Clone: 28P22

Détail du produit anti-P4HTM anticorps

Fonction: P4HTM Antibody / HIF Prolyl Hydroxylases / HIFPH4

Purification: Affinity chromatography

Immunogène: A synthetic peptide derived from human HIF Prolyl Hydroxylases was used as the immunogen for the P4HTM antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the P4HTM antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the P4HTM antibody at -20oC.

Détails sur P4HTM

Antigène: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Autre désignation: P4HTM

Sujet: Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. [UniProt]

UniProt: Q9NXG6