PRC1 anticorps

N° du produit ABIN7882088

Cet anticorps anti-PRC1 Monoclonal Lapin (Clone EH-16) (ABIN7882088) détecte spécifiquement PRC1 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PRC1 anticorps (ABIN7882088)

Antigène: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PRC1 est non-conjugé

Application: Western Blotting (WB)

Clone: EH-16

Détail du produit anti-PRC1 anticorps

Fonction: PRC1 Antibody

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human PRC1 was used as the immunogen for the PRC1 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the PRC1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the PRC1 antibody at -20oC.

Détails sur PRC1

Antigène: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Autre désignation: PRC1

Sujet: Protein regulator of cytokinesis 1 (PRC1) is a key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression. [UniProt]

UniProt: O43663