RAD21 anticorps

N° du produit ABIN7882129

L’anticorps anti-RAD21 Monoclonal Lapin est utilisé pour la détection de RAD21 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour RAD21 anticorps (ABIN7882129)

Antigène: RAD21 (RAD21 Homolog (RAD21))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp RAD21 est non-conjugé

Application: Western Blotting (WB)

Clone: CBH-18

Détail du produit anti-RAD21 anticorps

Fonction: Rad21 Antibody

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human Rad21 was used as the immunogen for the Rad21 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Rad21 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the Rad21 antibody at -20oC.

Détails sur RAD21

Antigène: RAD21 (RAD21 Homolog (RAD21))

Autre désignation: Rad21

Sujet: Double-strand-break repair protein rad21 homolog' is a cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway. [UniProt]

UniProt: O60216

Pathways: Positive Regulation of Endopeptidase Activity