Retinoid X Receptor gamma anticorps

N° du produit ABIN7882161

Cet anticorps Souris Monoclonal détecte spécifiquement Retinoid X Receptor gamma dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Retinoid X Receptor gamma anticorps (ABIN7882161)

Antigène: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Retinoid X Receptor gamma est non-conjugé

Application: Flow Cytometry (FACS)

Clone: PCRP-RXRG-5C9

Détail du produit anti-Retinoid X Receptor gamma anticorps

Fonction: RXR gamma Antibody / RXRG

Purification: Protein A/G affinity

Immunogène: Recombinant human RXR gamma protein was used as the immunogen for the RXRG antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the RXR gamma antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the RXR gamma antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur Retinoid X Receptor gamma

Antigène: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Autre désignation: RXR gamma

Sujet: Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RARa, RARb and RARg, each of which have a high affinity for all trans-retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand-binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXRa, RXRb and RXRg, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci.

UniProt: P78347

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway