Secretory Component anticorps

N° du produit ABIN7882222

L’anticorps anti-Secretory Component Monoclonal Souris est utilisé pour la détection de Secretory Component dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Secretory Component anticorps (ABIN7882222)

Antigène: Secretory Component

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Secretory Component est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SPM217

Détail du produit anti-Secretory Component anticorps

Fonction: Secretory Component Antibody / ECM1

Purification: Protein G affinity chromatography

Immunogène: Secretory Component protein isolated from human colostrum was used as the immunogen for this Secretory Component antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: The optimal dilution of the Secretory Component antibody for each application should be determined by the researcher.

1. Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10 mM Tris with 1 mM EDTA for 10-20 min followed by cooling at RT for 20 minutes.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Secretory Component antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Secretory Component

Antigène: Secretory Component

Sujet: This mAb reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression.

UniProt: Q16610