SNW1 anticorps

N° du produit ABIN7882290

Cet anticorps Souris Monoclonal détecte spécifiquement SNW1 dans IF et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SNW1 anticorps (ABIN7882290)

Antigène: SNW1 (SNW Domain Containing 1 (SNW1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SNW1 est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-SNW1-1C12

Détail du produit anti-SNW1 anticorps

Fonction: SNW1 Antibody / NCoA-62 / SKIP

Purification: Protein A/G affinity

Immunogène: A recombinant fragment of human SNW1 protein was used as the immunogen for the SNW1 antibody.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal dilution of the SNW1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the SNW1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur SNW1

Antigène: SNW1 (SNW Domain Containing 1 (SNW1))

Autre désignation: SNW1

Sujet: Nuclear receptor coactivator NCOA62/SNW1 (also called Nuclear Protein SkiP, SKIIP, Ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

UniProt: Q13573

Pathways: Retinoic Acid Receptor Signaling Pathway