SULT1E1 anticorps

N° du produit ABIN7882385

Cet anticorps anti-SULT1E1 Monoclonal Souris (Clone CPTC-SULT1E1-1) (ABIN7882385) détecte spécifiquement SULT1E1 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour SULT1E1 anticorps (ABIN7882385)

Antigène: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SULT1E1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: CPTC-SULT1E1-1

Détail du produit anti-SULT1E1 anticorps

Fonction: SULT1E1 Antibody / Estrogen Sulfotransferase (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: Recombinant human protein was used as the immunogen for the SULT1E1 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the SULT1E1 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the SULT1E1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur SULT1E1

Antigène: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Autre désignation: SULT1E1

Sujet: The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.

UniProt: P49888

Pathways: Steroid Hormone Biosynthesis