SULT1E1 anticorps

N° du produit ABIN7882387

L’anticorps anti-SULT1E1 Monoclonal Souris est utilisé pour la détection de SULT1E1 dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour SULT1E1 anticorps (ABIN7882387)

Antigène: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SULT1E1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CPTC-SULT1E1-1

Détail du produit anti-SULT1E1 anticorps

Fonction: SULT1E1 Antibody / Estrogen Sulfotransferase

Purification: Protein G affinity chromatography

Immunogène: Recombinant human protein was used as the immunogen for the SULT1E1 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the SULT1E1 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the SULT1E1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur SULT1E1

Antigène: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Autre désignation: SULT1E1

Sujet: The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.

UniProt: P49888

Pathways: Steroid Hormone Biosynthesis