Recombinant TSHB anticorps

N° du produit ABIN7882484

Cet anticorps anti-TSHB Monoclonal Lapin (Clone TSHb-7001R) (ABIN7882484) détecte spécifiquement TSHB dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant TSHB anticorps (ABIN7882484)

Antigène: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TSHB est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TSHb-7001R

Détail du produit anti-TSHB anticorps

Fonction: Recombinant TSH beta Antibody / TSHB

Purification: Protein A/G affinity

Immunogène: A recombinant human TSH beta protein fragment was used as the immunogen for the recombinant TSH beta antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the recombinant TSH beta antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the recombinant TSH beta antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur TSHB

Antigène: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Autre désignation: TSH beta

Sujet: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. TSH is synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3). TSH production is controlled by a Thyrotropin-Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release. TSH is a useful marker in classification of pituitary tumors and the study of pituitary disease.

UniProt: P01222

Pathways: Thyroid Hormone Synthesis, Peptide Hormone Metabolism