TSHB anticorps

N° du produit ABIN7882485

Cet anticorps Souris Monoclonal détecte spécifiquement TSHB dans IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour TSHB anticorps (ABIN7882485)

Antigène: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TSHB est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: TSHb-1317

Détail du produit anti-TSHB anticorps

Fonction: TSHB Antibody / TSH beta (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogène: A recombinant human partial protein was used as the immunogen for this TSHB antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the TSHB antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the TSHB antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur TSHB

Antigène: TSHB (Thyroid Stimulating Hormone, beta (TSHB))

Autre désignation: TSHB

Sujet: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH) follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. TSH is synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3). TSH production is controlled by a Thyrotropin-Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release. TSH is a useful marker in classification of pituitary tumors and the study of pituitary disease.

UniProt: P01222

Pathways: Thyroid Hormone Synthesis, Peptide Hormone Metabolism