TFF1 anticorps

N° du produit ABIN7882565

Cet anticorps anti-TFF1 Polyclonal Lapin (ABIN7882565) détecte spécifiquement TFF1 dans WB et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour TFF1 anticorps (ABIN7882565)

Antigène: TFF1 (Trefoil Factor 1 (TFF1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFF1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-TFF1 anticorps

Fonction: Estrogen Inducible Protein pS2 Antibody / TFF1

Séquence: FYPNTIDVPP EEECEF

Purification: Antigen affinity purified

Immunogène: Amino acids FYPNTIDVPPEEECEF from the human protein were used as the immunogen for the Estrogen Inducible Protein pS2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Estrogen Inducible Protein pS2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Estrogen Inducible Protein pS2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur TFF1

Antigène: TFF1 (Trefoil Factor 1 (TFF1))

Autre désignation: Estrogen Inducible Protein pS2

Sujet: TFF1 (Trefoil factor 1), also known as pS2, is a protein that in humans is encoded by the TFF1 gene. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. It is found that TFF1 in normal human urine inhibited the growth of calcium oxalate crystals. Urinary TFF1 showed an inhibitory potency similar to that of nephrocalcin, and inhibition was dose dependent and inhibited by TFF1 antisera, particularly by antisera directed to the TFF1 C terminus. Concentrations and relative amounts of TFF1 in the urine of patients with idiopathic calcium oxalate kidney stones were significantly less than those found in controls. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

UniProt: P04155

Pathways: EGFR Signaling Pathway