Recombinant WT1 anticorps

N° du produit ABIN7882702

L’anticorps anti-WT1 Monoclonal Souris est utilisé pour la détection de WT1 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant WT1 anticorps (ABIN7882702)

Antigène: WT1 (Wilms Tumor 1 (WT1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp WT1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MMWT1-1

Détail du produit anti-WT1 anticorps

Fonction: Recombinant Wilms Tumor 1 Antibody

Purification: Protein G affinity chromatography

Immunogène: A recombinant human protein was used as the immunogen for the recombinant Wilms Tumor 1 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Titering of the recombinant Wilms Tumor 1 antibody may be required for optimal performance.

2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant Wilms Tumor 1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur WT1

Antigène: WT1 (Wilms Tumor 1 (WT1))

Autre désignation: Wilms Tumor 1

Sujet: Wilms Tumor is a transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA. [UniProt]

UniProt: P19544

Pathways: Tube Formation