YTHDF2 anticorps

N° du produit ABIN7882713

Cet anticorps Lapin Polyclonal détecte spécifiquement YTHDF2 dans WB, IF, FACS et IHC (p). Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour YTHDF2 anticorps (ABIN7882713)

Antigène: YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YTHDF2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-YTHDF2 anticorps

Fonction: YTHDF2 Antibody

Séquence: NDDDFEPYLS PQARPNNAYT AMSD

Purification: Affinity purified

Immunogène: Amino acids NDDDFEPYLSPQARPNNAYTAMSD from the human protein were used as the immunogen for the YTHDF2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the YTHDF2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the YTHDF2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur YTHDF2

Antigène: YTHDF2 (YTH Domain Family, Member 2 (YTHDF2))

Autre désignation: YTHDF2

Sujet: YTH N6-methyladenosine RNA binding protein 2 is a protein that in humans is encoded by the YTHDF2 gene. This gene encodes a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosome 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

UniProt: Q9Y5A9