GHRH anticorps (AA 1-29)

N° du produit ABIN7884242

Cet anticorps anti-GHRH Polyclonal Mouton (ABIN7884242) détecte spécifiquement GHRH dans IHC, RIA et Imm. L’anticorps est réactif avec des échantillons de Rat.

Aperçu rapide pour GHRH anticorps (AA 1-29) (ABIN7884242)

Antigène: GHRH (Growth Hormone Releasing Hormone (GHRH))

Reactivité: Rat

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp GHRH est non-conjugé

Application: Immunohistochemistry (IHC), Radioimmunoassay (RIA), Immunogen (Imm)

Détail du produit anti-GHRH anticorps

Épitope: AA 1-29

Fonction: Growth Hormone-Releasing Hormone Sheep Polyclonal Antibody

Specificité: The antibody recognizes the rat GHRH and it shows no cross-reactivity with SRIF-14, SRIF-28 rGH, LH, FSH, PRL calcitonin, insulin, glucagon ovine CRF, secretin, vasoactive intestinal peptide, and cholecystokinin-8

Immunogène: synthetic rat GHRH (1-29)NH2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: If reconstituted with deionized water in 50 μL: IHC: 1:15000, In vivo Passive Immunization: neat serum, RIA: In a RIA for rGRF-(1043), at a final dilution of 1: 785,000, this antiserum binds 35 % of [125I]-rGRF and can detect 7pg/assay tube. Optimal dilution has to be determined by the user.

Buffer: Lyophilized serum

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.

Date de péremption: 24 months

Détails sur GHRH

Antigène: GHRH (Growth Hormone Releasing Hormone (GHRH))

Autre désignation: Growth Hormone-Releasing Hormone

Sujet:

GHRH, Somatocrinin, Somatoliberin, GH-RH, Growth hormone-releasing factor (GHRF or GRF), Somatotropin-releasing hormone (SRH), Somatotropin-releasing factor (SRF), Somatorelin

GHRH belongs to the glucagon family produced in the hypothalamus. It is essential for normal linear growth and has important metabolic effects throughout life. GHRH stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary. GHRH is released from neurosecretory nerve terminals of arcuate neurons, and is carried by the hypothalamo-hypophyseal portal system to the anterior pituitary gland, where it stimulates growth hormone(GH) secretion by stimulating the growth hormone-releasing hormone receptor.

Pathways: Hormone Transport, Hormone Activity, cAMP Metabolic Process