HIV-1 Transmembrane Glycoprotein (HIV-1 gp41) (AA 579-613) anticorps

N° du produit ABIN7884243

Cet anticorps Human Monoclonal détecte spécifiquement HIV-1 Transmembrane Glycoprotein dans ELISA, IP et ICo. Il présente une réactivité avec des échantillons de Human Immunodeficiency Virus (HIV).

Aperçu rapide pour HIV-1 Transmembrane Glycoprotein (HIV-1 gp41) (AA 579-613) anticorps (ABIN7884243)

Antigène: HIV-1 Transmembrane Glycoprotein (HIV-1 gp41)

Reactivité: Human Immunodeficiency Virus (HIV)

Hôte: Human

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: ELISA, Immunoprecipitation (IP), Immunocompetition (ICo)

Clone: 50-69

Détail du produit

Épitope: AA 579-613

Fonction: HIV-1 (gp41) Human Monoclonal Antibody (50-69)

Specificité: The antibody recognizes the HIV-1 protein gp41. (amino acids 579-613)

Purification: Protein G purified

Immunogène: The antibody was generated from HIV-infected individuals by a method based on the Epstein-Barr virus transformation of peripheral blood mononuclear cells (PBMCs) followed by fusion with heteromyeloma cells.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water. Optimal dilution has to be determined by the user.

Buffer: Lyophilized protein G purified in PBS pH 7.4

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.

Date de péremption: 24 months

Détail du antigène

Antigène: HIV-1 Transmembrane Glycoprotein (HIV-1 gp41)

Autre désignation: HIV-1 (gp41)

Classe de substances: Viral Protein

Sujet: Of the two types of Human immunodeficiency virus (HIV) which have been characterized, HIV-1 is more infective and is prevalent globally. The HIV virion is encapsulated by a viral envelope that contains complexes of surface proteins, which are important for the virus to attach and fuse to infect target cells. A precursor molecule known as gp160 (glycoprotein 160) is cleaved by proteases into gp120 (glycoprotein 120) and gp41 (glycoprotein 41), glycoproteins that make up the envelope proteins of HIV. Glycoprotein gp41 is embedded in the viral membrane and can interact with other gp41 proteins. The proteins gp41 and gp120 form a complex which is thought to undergo conformational changes in order to initiate membrane fusion of the virus with a cell.