Aquaporin 5 anticorps (C-Term, Intracellular)

N° du produit ABIN7884769

L’anticorps anti-Aquaporin 5 Polyclonal Lapin est utilisé pour la détection de Aquaporin 5 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC, IF et IC.

Aperçu rapide pour Aquaporin 5 anticorps (C-Term, Intracellular) (ABIN7884769)

Antigène: Aquaporin 5 (AQP5)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aquaporin 5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunochromatography (IC)

Classe de qualité: Carrier-free

Détail du produit anti-Aquaporin 5 anticorps

Épitope: AA 251-265, C-Term, Intracellular

Fonction: A Rabbit Polyclonal Antibody to Aquaporin 5 Channel

Homologie: Mouse - identical, human - 10,16 amino acid residues identical

Purification: Affinity purified on immobilized antigen.

Immunogène: (C)DHREERKKTIELTAH corresponding to amino acid residues 251-265 of rat AQP5

Isotype: IgG

Information d'application

Indications d'application:

WB: 1:200

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: The optimal concentration should be determined by the user

IP: The optimal concentration should be determined by the user

Commentaires:

Negative Control: (ABIN7234767)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 0.2 mL double distilled water (DDW)

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Détails sur Aquaporin 5

Antigène: Aquaporin 5 (AQP5)

Autre désignation: AQP5

Sujet:

Synonyms: AQP5

Description: The importance of the aquaporin water channels was underscored by awarding the 2003 Nobel Prize in Chemistry to Peter Agre "for the discovery of water channels". Today, eleven mammalian proteins that belong to the aquaporin family have been identified. The proteins present a conserved structure of six transmembrane domains with intracellular N- and C-termini. Aquaporin 5 (AQP5) is expressed in secretory glands, lung and eye, where it works in modulating the rate of fluid release. Since a number of pathological conditions including pulmonary edema, respiratory distress syndrome and congestive heart failure are characterized by disrupted fluid transport, it has been suggested that modulation of the expression of AQP5 could be a novel modality of treatment of the above illnesses. Indeed, several studies have shown that AQP5 expression is downregulated in animal models of acute lung infection.

ID gène: 25241

UniProt: P47864