AQP9 anticorps (Intracellular, N-Term)

N° du produit ABIN7884773

Cet anticorps anti-AQP9 Polyclonal Lapin (ABIN7884773) détecte spécifiquement AQP9 dans WB et IHC. L’anticorps est réactif avec des échantillons de Souris et Rat.

Aperçu rapide pour AQP9 anticorps (Intracellular, N-Term) (ABIN7884773)

Antigène: AQP9 (Aquaporin 9 (AQP9))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AQP9 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Classe de qualité: Carrier-free

Détail du produit anti-AQP9 anticorps

Épitope: AA 4-19, Intracellular, N-Term

Fonction: A Rabbit Polyclonal Antibody to Aquaporin 9 Channel

Homologie: Mouse - 13,16 amino acid residues identical

Purification: Affinity purified on immobilized antigen.

Immunogène: (C)EKDGAKKSLMQRLALK, corresponding to amino acid residues 4-19 of rat AQP9

Isotype: IgG

Information d'application

Indications d'application:

WB: 1:200

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: 1:100

IP: The optimal concentration should be determined by the user

Commentaires:

Negative Control: (ABIN7234783)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 0.2 mL double distilled water (DDW)

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Détails sur AQP9

Antigène: AQP9 (Aquaporin 9 (AQP9))

Autre désignation: AQP9

Sujet:

Synonyms: AQP9, Aquaglyceroporin-9

Description: Aquaporin 9 (AQP-9) belongs to a family of membrane proteins that allow passage of water and certain other solutes through biological membranes.1 The family is composed of 13 members (AQP-0 to AQP-12). Little is known about the function of the two newest members, AQP-11 and AQP-12.The aquaporins can be divided into two functional groups based on their permability characteristics: the aquaporins that are permeated primarily by water (AQP-1, AQP-2, AQP4, AQP-5, AQP-6, AQP-8), and the aquaglyceroporins that are permeated by water and other small solutes such as glycerol. This last group includes AQP-3, AQP-7, AQP-9 and AQP-10.The proteins present a conserved structure of six transmembrane domains with intracellular N- and C-termini. The functional channel is a tetramer but each subunit has a separate pore and therefore the functional channel unit contains four pores.2AQP-9 is expressed in several tissues including the brain, liver, testis and spleen. In the liver AQP-9 has a central role in glycerol metabolism as demonstrated in experiments using AQP-9 knockout mice: mice deficient in AQP-9 expression showed enhanced plasma levels of glycerol and triglycerides.3

ID gène: 65054

UniProt: P56627