Chloride Channel 5 anticorps (Extracellular)

N° du produit ABIN7884875

Cet anticorps anti-Chloride Channel 5 Polyclonal Lapin (ABIN7884875) détecte spécifiquement Chloride Channel 5 dans WB et IHC. L’anticorps est réactif avec des échantillons de Rat et Souris.

Aperçu rapide pour Chloride Channel 5 anticorps (Extracellular) (ABIN7884875)

Antigène: Chloride Channel 5 (CLCN5)

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Chloride Channel 5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Classe de qualité: Carrier-free

Détail du produit anti-Chloride Channel 5 anticorps

Épitope: AA 401-415, Extracellular

Fonction: A Rabbit Polyclonal Antibody to CLC-5 (CLCN5) Channel

Homologie: Mouse - identical, human - 14,15 amino acid residues identical

Purification: Affinity purified on immobilized antigen.

Immunogène: CDYENHFNTSKGGEL, corresponding to amino acid residues 401-415 of rat CLCN5 

Isotype: IgG

Information d'application

Indications d'application:

WB: 1:200

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: The optimal concentration should be determined by the user

IP: The optimal concentration should be determined by the user

Commentaires:

Negative Control: BLP-CL003

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 0.2 mL double distilled water (DDW)

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Détails sur Chloride Channel 5

Antigène: Chloride Channel 5 (CLCN5)

Autre désignation: CLCN5

Sujet:

Synonyms: CLCN5, Chloride channel 5, Chloride transporter ClC-5, H+/Cl- exchange transporter 5, DENTS

Description: CLC5 is a member of the voltage-dependent Cl- channel family that includes nine known members. Based on sequence similarity, CLC5 is closely linked to the CLC3 and CLC4 subunits. CLC-5 is mainly found in intracellular vesicles, particularly in early endosomes, where it is believed to contribute to their acidification.The channel is mainly expressed in the kidney, although it has also been found in the small intestine, brain and liver.Mutations in the CLC5 gene cause Dent's disease, an X-linked renal disorder.

ID gène: 25749

UniProt: P51796