GPR174 anticorps (Extracellular Loop)

N° du produit ABIN7884975

Cet anticorps Lapin Polyclonal détecte spécifiquement GPR174 dans WB, FACS et LCI. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour GPR174 anticorps (Extracellular Loop) (ABIN7884975)

Antigène: GPR174 (G Protein-Coupled Receptor 174 (GPR174))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPR174 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Live Cell Imaging (LCI)

Classe de qualité: Carrier-free

Détail du produit anti-GPR174 anticorps

Épitope: AA 160-175, Extracellular Loop

Fonction: A Rabbit Polyclonal Antibody to GPR174

Homologie: Human - 15,16 amino acid residues identical, mouse,rat - 13

Purification: Affinity purified on immobilized antigen.

Immunogène: (C)DTSGNRTK(S)FVDLPTR, corresponding to amino acid residues 160 - 175 of human GPR174

Isotype: IgG

Information d'application

Indications d'application:

WB: 1:400

FC: 5 μg per reaction

ICC: The optimal concentration should be determined by the user

IHC: The optimal concentration should be determined by the user

IP: The optimal concentration should be determined by the user

Commentaires:

Negative Control: (ABIN7235384)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 0.2 mL double distilled water (DDW)

Concentration: 1 mg/mL

Buffer: PBS pH 7.4

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Détails sur GPR174

Antigène: GPR174 (G Protein-Coupled Receptor 174 (GPR174))

Autre désignation: G-protein coupled receptor 174

Sujet:

Synonyms: G-protein coupled receptor 174, LYPSR3, GPCR17, FKSG79

Description: GPR174 (LysoPS, LYPSR3), is one of three lysophosphatidyl serine receptors, belonging to the superfamily of G-protein coupled receptors. Lysophospholipids are a diverse group of small, membrane-derived phospholipids that act as extracellular signals1.Activation of GPR174 leads to an increase in cAMP cellular levels, leading to cellular morphological changes, cell to cell adhesion, and delays in cell proliferation2.GPR174 is reported to be a genetic risk locus for Graves disease, an autoimmune disorder that causes hyperthyroidism3 and as a negative regulator of T-cells activation4.

ID gène: 84636

UniProt: Q9BXC1